Dr. Yu-Waye (Wayne) Chu is Senior Vice President, Clinical Development at Fate Therapeutics, overseeing the company’s clinical development strategies. Prior to joining Fate, Wayne assumed roles of increasing responsibility in Product Development Oncology at Genentech since 2009, where he worked on the development of the HER2-directed antibody drug conjugate trastuzumab emtansine (Kadcyla). He joined the Early Clinical Development group in Genentech Research and Early Development (gRED) in 2011 where he led the early clinical development of molecules spanning multiple therapeutic platforms including antibody drug conjugates, checkpoint inhibitors, and immune cell bispecific antibodies, notably the development of polatuzumab vedotin (anti-CD79b antibody drug conjugate), tiragolumab (anti-TIGIT monoclonal antibody) and mosunetuzumab (CD20/CD3 bispecific antibody), and continued to lead the global development of mosunetuzumab in Product Development Oncology at Roche/Genentech. Dr. Chu conducted his clinical training in pediatric hematology-oncology at Johns Hopkins School of Medicine and the National Cancer Institute. His major clinical and research interests included hematopoietic stem cell transplantation for the treatment of pediatric cancers, and T-cell biology with a focus on T-cell development and maturation, T-cell homeostasis and immune reconstitution following stem cell transplant. Dr. Chu graduated cum laude with a B.A. in Molecular Biology from Princeton University, and earned his M.D. with Distinction in Research from the University of Rochester School of Medicine and Dentistry.
Dr. Wen Bo Wang is Senior Vice President, Technical Operations at Fate Therapeutics, overseeing the company’s manufacturing strategies for its pipeline of off-the-shelf cell-based cancer immunotherapy candidates and scaling the Company’s induced pluripotent stem cell iPSC platform to support late-stage clinical and commercial operations. She was formerly Senior Vice President Cell Therapy R&D at Fujifilm Cellular Dynamics Inc (FCDI), where she was responsible for developing the cell therapy R&D strategy and the iPSC based pipeline products and led the next generation production technology development efforts. Previously, she was VP Process Sciences, and directed scale up and scale out platform process development for iPSC based iCell products and MyCell products including automation and bioreactor work. Prior to joining FCDI in 2008, Dr. Wang was Group Leader, Process Sciences, at Geron Corporation, Menlo Park, CA working with embryonic stem cell derived cell therapies and dendritic cell cancer vaccine. From 2001 to 2005, Dr Wang held a number of positions at ViaCell, Boston, MA including Associate Scientific Director, ViaCord Human Umbilical Cord Blood Bank (a subdivision of ViaCell). Dr. Wang serves on the board of directors for Standards Coordinating Body and as US expert at the US Technical Advisory Group (US TAG) for ISO TC/276 Biotechnology. Dr. Wang earned a B.S. in Biology from Ocean University of Qingdao, P.R. China and received her Ph.D. in Biology from Newcastle University, United Kingdom. She conducted post-doctoral training in Cryobiology at Biosciences Research Laboratory, USDA/Agricultural Research Service, Fargo, N.D.
Sarah Cooley, M.D., M.S. is Senior Vice President, Clinical Translation at Fate Therapeutics and oversees translational medicine across the cell-based cancer immunotherapy programs and for early clinical development of cell product candidates. Dr. Cooley, an expert in the field of natural killer (NK) cell receptor immunogenetics and in the clinical development of NK cell cancer immunotherapies, brings to Fate Therapeutics more than 12 years of leadership in the field of NK cell clinical research and development. Prior to joining Fate, she was an Associate Professor of Medicine in the Division of Hematology, Oncology and Transplantation at the University of Minnesota where her clinical practice included adult Hematologic Malignancy and Blood and Marrow Transplant service and her research included leading 15 clinical trials of NK cell or immunotherapy-based cancer treatments. At the University of Minnesota’s Masonic Cancer Center, Dr. Cooley played a critical role in the development of translational research infrastructure, serving as the Medical Director for the Clinical Trials Office, for the Oncology Informatics Shared Resource and as Director of the Cancer Research Translational Initiative. Dr. Cooley received an undergraduate degree in Biology and Chemistry from Cornell University and graduated from the University of Minnesota Medical School. She completed a residency in Internal Medicine at the University of California, San Francisco and fellowship training in Hematology and Oncology at the University of Minnesota, where she also received her M.S. in Clinical Research from the School of Public Health.
Mr. Beitel is Senior Vice President, Corporate Development, at Fate Therapeutics and is responsible for developing and implementing strategic growth initiatives including expanding the company’s induced pluripotent stem cell (iPSC)-derived cell therapy pipeline through corporate partnerships. Mr. Beitel has more than 20 years of leadership experience in corporate development, strategy, sales and marketing, project management and finance with experience across the spectrum of life science companies. Mr. Beitel was previously Vice President of Corporate Development and Operations at Avanir Pharmaceuticals, where he facilitated the company’s growth into a multi-product organization and the subsequent acquisition of Avanir by Otsuka. Prior to Avanir, Mr. Beitel held various business development, sales and marketing, strategy and finance roles with increasing responsibility at Amgen, La Jolla Pharmaceutical Company and Zacharon Pharmaceuticals. Mr. Beitel holds a Master in Business Administration from Harvard Business School and a Bachelor of Science in Engineering from the University of Kansas.